BillionToOne is a next-generation molecular diagnostics company dedicated to developing powerful and accurate diagnostic tests that are accessible to all. Our innovative QCT molecular counting technology significantly enhances the resolution of disease detection using cell-free DNA by over a thousandfold. This groundbreaking technology is integral to our product offerings, including one of our flagship products, Unity Complete™, the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Leveraging the same molecular counting technology, we've expanded our impact into oncology in 2023 with a pioneering liquid biopsy test, Northstar, that combines treatment selection with monitoring. To date, over 500,000 patients have benefited from our innovative and precise diagnostic tests, and our Annual Recurring Revenue (ARR) has grown from $0 to $125 million in the last ~4 years.
BillionToOne has successfully raised close to $400 million in funding, with a notable $130 million Series D round completed in June 2024, resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. BillionToOne has recently been recognized by Forbes as one of America's Best Startup Employers for 2024, highlighting the company's exceptional work environment and commitment to innovation.
Our team has grown significantly and we now proudly employ over 400 highly skilled individuals. Despite substantial growth, we have successfully maintained the unique culture that has defined BillionToOne from inception, continuing to cultivate a team that is not only diverse and passionate but also innovative. Headquartered in Menlo Park, California, with an additional facility in Union City, California, BillionToOne remains at the forefront of significant advances in molecular diagnostics, evidenced by the recent announcement of clinical outcomes data for its Unity Fetal Risk Screen and new advancements in cancer diagnostics. For more detailed information about BillionToOne and its groundbreaking work, please visit our website at www.billiontoone.com.
We are looking for a talented Translational Research Associate for our Oncology Clinical Affairs team. You will drive clinical study analysis in a vertically integrated manner, from coordinating samples with our lab operations all the way to publications. Our groundbreaking Northstar oncology assays detect tumor derived mutated and methylated DNA with a simple blood draw; this role is crucial in demonstrating the clinical validity of our Northstar assays. You will advance the success of our Northstar assays by solving meaningful challenges at the intersection of computer science, statistics, genomics, and medicine. You will be at the forefront of molecular diagnostic technology as part of a team passionate about fighting cancer.
This is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. The Translational Research Associate role is a hybrid position in our Menlo Park, CA facility.
Responsibilities:
- Design, execute, and validate automated scripts for managing and organizing diverse data corresponding to large clinical studies, including bioinformatic next generation sequencing (NGS) results and longitudinal clinical health records.
- Build, maintain, and execute analytic pipelines combining molecular and clinical results, which will include data cleaning, statistical analysis, oral and written presentation of results.
- Devise and apply appropriate statistical methods on time-series molecular and clinical measurements.
- Collaborate with internal and external stakeholders to advance ongoing clinical studies and provide analytical insights.
- Summarize findings orally and in writing, internally and externally.
- Contribute to poster and publication preparation; attend conferences.
Requirements:
- Education: Bachelor’s or Master’s in Computer Science, Biostatistics, statistics or related field.
- Experience: Bachelor’s with least 1-2 years of experience in a research or clinical setting or a Master’s in a relevant field.
- Communication: Exceptional written and verbal communication skills. Ability to work collaboratively with internal and external stakeholders with diverse specializations in business, translational research, clinical research, bioinformatics, and benchwork.
- Technical: Proficiency in python or R. Experience with large data sets and data pipeline engineering. Ability to efficiently retrieve, modify, merge, and summarize data from disparate sources and across a multitude of formats.
- Statistics: Strong fundamental knowledge including hypothesis testing, statistical distributions, confounders, and multiple test correction.
- Genetics: Conceptual understanding of somatic variation, germline variation, epigenetics and corresponding lab technologies such as PCR and NGS.
- “Dry lab” experience is required. This may include the statistical analysis of biological, genetic, or clinical data.
Nice-to-Haves
- Experience: analyzing clinical studies or clinical trials; translational cancer research; one or more peer-reviewed publications in oncology.
- Technical: git, github, AWS, S3, SQL, Redcap, OCR, LLMs, machine learning.
- Statistics: Kaplan Meier curves, hazard ratios, time series analysis.
- Regulatory Knowledge: Experience in diagnostics test and/or drug regulatory approval process. Familiarity with HIPAA regulations.
- Genetics: Familiarity with cancer biology, aneuploidy, copy number variation, circulating tumor DNA (ctDNA), cell-free DNA (cfDNA).
- Clinical: Experience with clinical studies, RECIST, radiology, oncology, pharmacology, or pathology.
Benefits And Perks:
- Working with a team of ‘rockstars’ who bring out the best in everyone
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Retirement savings program including a 4% Company match
- Free daily on-site lunches provided from top eateries
- Latest and greatest hardware (laptop, lab equipment, facilities)
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, the base pay range is: $70,000-$80,000 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Top Skills
What We Do
BillionToOne is a precision diagnostics company with the mission to make molecular diagnostics more accurate, efficient, and accessible for all. Our patent-pending molecular counter platform is the only technology platform that can accurately count the DNA molecules at the single-count level.
