Hematology Intern

Posted 3 Days Ago
Be an Early Applicant
Cambridge, MA
Internship
Biotech • Pharmaceutical
The Role
As a Hematology Intern at Beam Therapeutics, you will engage in primary cell culture, assist in platform assay development, and master transfection techniques. You'll prepare samples for Next-Generation Sequencing and document findings while learning and adapting in a collaborative environment.
Summary Generated by Built In

Company Overview:

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform that includes a suite of gene editing and delivery technologies and is in the process of building internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of potential therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Position Overview:

Beam Therapeutics is in search of a self-motivated intern to join our Hematology team from June through August 2025. This is a unique opportunity to contribute to groundbreaking work in the field of gene editing and hematopoietic stem cell research.

Responsibilities:

As a member of our team, you will play a crucial role in advancing our mission. Your responsibilities will include:

  • Primary Cell Culture: Engage in primary cell culture and immortalized cell line culture activities, including feedings, passaging, and freezing.
  • Platform Assay Development: Participate in the development of platform assays, testing new materials and protocols to enhance our research capabilities.
  • Transfection: Master the art of transfecting primary hematopoietic stem cells and cell lines with Lipid Nanoparticles (LNPs), a cutting-edge technology.
  • Sample Preparation: Prepare samples for Next-Generation Sequencing (NGS) and other downstream analyses, ensuring the accuracy and integrity of our data.
  • Documentation and Communication: Document your findings meticulously, summarize your studies, and present your results to internal audiences, contributing to the collective knowledge of our team.
  • Continuous Learning: Embrace the opportunity to learn and adapt, acquiring new techniques and skills that make you a versatile, cross-functional asset.

Qualifications:

To excel in this role, you should possess the following qualifications:

  • Educational Pursuit: Currently pursuing an MS or PhD in biology, biochemistry, biomedical engineering, or a related field of study.
  • Cell Culture Proficiency: Prior experience with mammalian cell culture is required. Primary human cell culture experience is desirable. Experience in isolating primary immune cells using magnetic cell sorting is a plus.
  • Flow Cytometry: Previous experience with multi-parameter flow cytometry is preferred.
  • Gene Editing: Prior experience or knowledge of gene editing technologies, such as CRISPR, will be beneficial.
  • Transfection: Knowledge of LNP or lipofectamine transfection protocols is a plus.
  • Team Player: Thrive in a collaborative environment and feel at home working alongside a dynamic team.
The Company
HQ: Cambridge, Massachusetts
488 Employees
On-site Workplace
Year Founded: 2017

What We Do

Beam Therapeutics, launched in 2018, is pioneering the use of CRISPR base editing to develop a broad portfolio of advanced genetic medicines. Our groundbreaking base editing technology allows us to make permanent, specific edits to single bases in DNA and RNA, without cutting the strands. Base editor therapeutics represent a new class of “precision genetic medicines,” combining precision targeting of the genome with precision control of editing outcomes.

Our dream is to provide life-long cures for patients suffering from serious diseases.

The Beam Team Is:
• A community of fearless innovators
• Rigorous and honest in our research
• Listening with open minds
• Committed to each other

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