About Plexium:
Plexium is the premier, next-generation Targeted Protein Degradation (TPD) company focused on the discovery of TPD drugs which overcome limitations of conventional approaches to broaden the therapeutic potential of TPD. Plexium is pursuing monovalent degraders, including a new class of selective TPD drugs called “Direct Degraders.” Direct Degraders are small molecules that are designed to bind to a pathogenic protein in a manner that results in selective degradation of the protein by the cell’s natural protein quality control machinery. In addition to direct degraders, Plexium is pursuing molecular glue degraders. This approach also leverages the cell’s natural quality control machinery, however in this case, small molecules bind to an E3 ligase, redirecting the ligase to selectively target pathogenic proteins for degradation. Plexium is pursuing drug targets that have previously been undruggable or inadequately drugged across multiple disease areas.
Plexium is powered by its proprietary TPD drug discovery platform which integrates degrader chemistry design principles and screening libraries with cell-based, target-specific degradation assays, including an ultra-high-throughput screening platform, to enable the identification of drug-like, cell-permeable degrader molecules. This integrated TPD drug discovery approach has led to the discovery of novel, selective direct degraders and molecular glue drug candidates, and two unprecedented E3 ligases.
Job Responsibilities
- Responsible for consolidated financial results by overseeing monthly and quarterly financial close processes, including review of key areas of judgment, key general ledger account reconciliations (including R&D accruals), and consolidation process to ensure the accurate and timely preparation of the Company’s consolidated financial statements
- Preparation of GAAP financial statements for internal and external reporting
- Responsible for key technical accounting judgments and policies, including oversight, implementation and execution of new accounting pronouncements
- Manage relationship with the Company’s external auditor. Ensure the integrity and accuracy of information provided to the external auditor in relation to the annual audit
- Cash management and treasury
- Oversee procure-to-pay function
- Oversee the administration of the Company’s 401(k) plan, ensuring compliance with regulatory requirements, reporting, and coordinating audits to maintain the plan’s integrity
- Preparation and maintenance of annual budgets, quarterly reforecasts, drywell analysis and other long-term planning
- Drive timely and accurate reporting to monitor monthly and quarterly financial changes, headcount, forecast, capital expense tracking, and other financial reporting
- Management of stock plan administration and accounting
- Interface with external tax advisors on relevant tax matters, including preparation of federal and state tax returns and tax provision
- Support evaluation, design, implementation, and maintenance of financial systems and system upgrades
- Undertake and manage special projects, as needed
Competencies
- Demonstrable experience managing the monthly/quarterly accounting close process
- Strong knowledge of US GAAP, technical accounting and SOX principles is required
- Detail oriented self-starter with ability to think strategically and effectively prioritize while managing various projects simultaneously
- Possess excellent decision-making skills and can act and operate independently with minimal direction to accomplish objectives
- Excellent verbal and written communication skills, ability to work collaboratively with other parts of the business including key internal/external stakeholders, investors and executive leadership
- Proficient in Microsoft Office Suite (Word, Outlook, Excel and PowerPoint), and the ability to learn new software programs
Education and Experience Requirements
- Bachelor’s degree in Accounting, Finance, or relevant field, with a minimum of 10 years of experience in a public company or public accounting role, showing a deep understanding of financial operations
- At least 3 years of experience managing a staff
- CPA certification is required
- Prior experience working in a biotechnology or pharmaceutical company is required
- Experience with core financial systems, including NetSuite, Coupa, Carta and Planful experience preferred
The US base salary range for this full-time position is $175,000 - $210,000 + target annual bonus + equity + health and well-being benefits. Our salary ranges are determined by a number of factors, including but not limited to the role, location, job-related skills, and relevant education, experience and training. The range displayed on each job posting reflects the minimum and maximum target for new hire base salaries for the position across all US locations and vary by the location of the position. Our Human Resources Team can share more about our salary ranges and other benefits of working at Plexium, which are not included in the posted base salary range.
Notice to third party recruitment agencies: Plexium does not accept unsolicited resumes from recruiters or employment agencies. In the absence of an executed recruitment services agreement, there will be no obligation to any referral compensation or recruiter fee. In the event a recruiter or agency submits a resume or candidate without an agreement Plexium shall explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency. Any unsolicited resumes, including those submitted to hiring managers, shall be deemed the property of Plexium.
Top Skills
What We Do
Plexium is a drug development startup that leverages techniques from various physical-science and computational disciplines.
