Nabsys

Nabsys uses proprietary electronic nano-channel detectors to analyze long DNA molecules at high velocity. Electronic detection enables Nabsys to achieve significantly higher resolution than can be obtained using optical mapping methods.

Nabsys HD-Mapping™ solid-state electronic nano-channel detectors build whole genome maps with sub-diffraction-limit resolution that are truly high definition. These maps offer compelling advantages for the analysis of structural variation, the assembly of genomes, and as a method for confirming putative variants called using other technologies.

HD-Mapping works by adding sequence-specific tags to long DNA molecules. These molecules pass through the nano-detectors at high velocity using a combination of electrophoretic and hydrodynamic control. The detectors report the locations of the sequence-specific tags on the molecules. The information is then analyzed by Nabsys analytical software.

Key application areas that are enabled by Nabsys include:
• De Novo Assembly
• Structural Variant Discovery
• Variant Verification
• Microbiome Analysis
• Metagenome Characterization
• Hybrid Assembly

Nabsys provides the complete solution for electronic genome mapping.
The Nabsys HD-Mapping platform includes:
• HD-Mapping instrument
• Electronic nano-channel detector chips
• Complete run reagent cartridge
• Sample prep kit
• Comprehensive control and data analysis software

Nabsys HD Mapping provides routine, accurate, cost-effective analysis of genomic structural information. The HD-Mapping platform employs fully electronic detection of tagged single DNA molecules to provide significantly higher sensitivity, accuracy, scalability and speed of detection in comparison to existing mapping technologies. Single-molecule reads, hundreds of kilobases in length, have high resolution and low error rates, resulting in high information content per read.