At Fujifilm Diosynth Biotechnologies, we are at the forefront of innovation, dedicated to enhancing and advancing biotechnological solutions. We are seeking a highly skilled Scale-Up Engineer to join our dynamic upstream team. This pivotal role involves utilizing your expertise in modeling and simulation of cell culture processes to propel our projects towards success!
About the job
The Upstream Scale-Up Engineer will be primarily responsible for employing advanced modeling and simulation techniques to scale-up and optimize cell culture processes. This role exists to ensure the efficient transition of processes from small scale to commercial scale, enhancing productivity and consistency in our production bioreactors.
We offer an exciting and challenging job. As no two clients are the same, you will get the chance to work with a broad range of biopharma companies from across the world, whilst deploying industry leading technologies and equipment to run the labs.
Key Responsibilities:
- Develop and implement models for scaling up cell culture processes from donor site bioreactors to bioreactors at various sites across the FDB network, ensuring optimal mass transfer and hydrodynamic conditions in bioreactors at production scale.
- Collaborate with cross-site Process Development Teams to translate laboratory processes to pilot and production scales processes, in the context of our KojoX initiative.
- Analyze data and generate comprehensive reports on process performance in large-scale bioreactors, identifying areas for process improvement for ongoing programs in the production pipeline.
- Plan and execute characterization study of bioreactor assets within Fujifilm Diosynth Biotechnologies. This includes use of computational fluid dynamic (CFD) models as part of routine equipment characterization activities.
- Stay abreast of the latest advancements in bioreactor design and simulation literature to enhance current methodologies.
Minimum Education Requirements:
- A Ph.D. or Master's degree in Chemical Engineering or Biochemical Engineering.
Minimum Experience Requirements:
- At least 5 years of experience in Process Development of Cell Culture processes in bioreactors or running production scale cell culture processes in Single Use Bioreactors, Bench top bioreactors and preferably large scale stainless steel bioreactors.
- Modeling and simulation of fermentation or cell culture processes, focusing on the impact of mass transfer and hydrodynamics on microbial/mammalian cell growth and performance.
- Proven experience with scale-up in a biotechnological setting.
- Proficiency in MATLAB, Python or VBA is a significant advantage.
Knowledge & Skills:
- Deep understanding of mass transfer and hydrodynamics within bioreactor systems.
- Strong analytical and problem-solving skills.
- Effective communication skills for presenting data internally/externally and collaborating within teams.
We Hope You Are
Structured in your way of working, can prioritize timelines and you thrive in an agile working environment with great flexibility. We hope you are ready to take up challenges and can handle several tasks at the same time.
Your New Team & Department
The Drug Substance Process Science organization consists of 5 teams: Cell Culture (Upstream), Purification (Downstream), Tech Transfer, Process Data Analytics and Material Science. With over 50 persons in the department from more than 10 countries, you will be part of a very dynamic and vibrant international organization.
The upstream group consists of a dedicated and skilled team of 13 scientists and 5 technicians. And we are still expanding.
We are team players, entrepreneurs, and people who both like details and take greater responsibility beyond our scope of work. The work environment is international and informal. We keep a high pace and focus on a vital work life balance while having fun. We put a strong emphasis on psychological safety through trust and empowerment within our teams and hope that this is something that speaks to you as well.
Your application
Has this sparked your interest, then please upload your CV and cover letter. Interviews will be conducted on an ongoing basis, so please apply as soon as possible.
The Company
FUJIFILM Diosynth Biotechnologies is an industry-leading Biologics Contract Development and Manufacturing Organization (CDMO) with locations in Hillerød, Denmark, Teesside, UK, RTP, North Carolina and College Station, Texas, USA. We use our skills, dedication, and ambition to enable impact for the world’s most innovative biotech and biopharma companies reimagining healthcare’s potential. We work across the entire lifecycle of our customers’ products – enabling success throughout. Every cure, vaccine, biologic, and advancement we contribute to starts with our people and our passion. We fuel one another’s passion, help accelerate progress, expand capabilities, strengthen innovation, and improve processes to improve lives.
We offer the chance to be part of a global workplace where passion, drive and commitment are met with opportunities for professional and personal development. Deeply committed to diversity and inclusion, we ensure that everyone no matter their background or gender has an opportunity to develop. We take pride in enriching our communities, caring for our environment, and cultivating a world of opportunity for future generations.
We aim to foster a collaborative, innovative and rewarding environment, where diverse perspectives and people come together united by a common purpose and shared values. We pursue our fullest potential as individual contributors and team members. We strive to be the employer of choice and offer a competitive compensation and benefit package.
FUJIFILM Diosynth Biotechnologies Denmark (FDBD) is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, disability, sexual orientation, gender identify or any other protected class.
To all agencies: Please, no phone calls or emails to any employee of FUJIFILM about this requisition. All resumes submitted by search firms/employment agencies to any employee at FUJIFILM via-email, the internet or in any form and/or method will be deemed the sole property of FUJIFILM, unless such search firms/employment agencies were engaged by FUJIFILM for this requisition and a valid agreement with FUJIFILM is in place. In the event a candidate who was submitted outside of the FUJIFILM agency engagement process is hired, no fee or payment of any kind will be paid.
Top Skills
What We Do
For over 30 years, FUJIFILM Diosynth Biotechnology’s mission has been advancing tomorrow’s medicine. As a CDMO, we work in partnership with the most innovative biopharma and biotech companies across the world who are reimagining healthcare’s potential. We help to accelerate their progress, expand their capabilities, streamline their processes, and strengthen their innovation. So when our customers’ potential cures, vaccines, biologics, and accomplishments make strides – or even become new realities for patients – we know our work, our manufacturing expertise, and our partnership helped make it happen.
FDB isn’t simply a workplace. It’s a place of passion – a place of what we call Genki. A place where diverse perspectives and people come to life. Where opportunity for growth has no end. Where passion is followed, discovered, and nurtured. Where the energy is undeniable, enthusiasm is pervasive, and drive is infectious. All of our global locations burst with curiosity, inspiration, and extraordinary purpose.
So as we continue to grow our teams, our global locations, and our capabilities, Genki will always be our cultural tie. That’s why we’re always looking for passionate, mission-driven people who want to commit their life’s work to enabling better outcomes for patients and their families.
For a full listing of jobs that will propel, inspire, and fulfill you, please visit: fujifilmdiosynth.com/careers/
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