Job Description
General Summary:
Vertex Pharmaceuticals is seeking a talented leader to join our Analytical Development team in Boston, MA. As the Sr. Principal Scientist, you will play a central role in advancing transformative medicines through all stages of clinical development. You will lead a team of technical experts dedicated to small molecule and synthetic peptide/oligonucleotide analytical development activities, providing scientific leadership and fostering team development.
Key Duties and Responsibilities:
- Lead a team of talented analytical development scientists, cultivating their growth and development.
- Oversee the development and validation of core analytical methods, with a focus on chromatographic techniques.
- Collaborate with project teams to design, oversee and review relevant analytical methods, validation protocols and reports for programs across all phases of development.
- Drive continuous improvement initiatives related to phase-appropriate method development and validation practices within Analytical Development.
- Ensure the compliance and consistency of method development and validation practice within the organization.
- Assist with training of staff and development of organizational expertise on method development and validation.
- Perform other duties as assigned.
Knowledge and Skills:
- Demonstrated leadership experience in a pharmaceutical or biotechnology setting
- Extensive experience in the space of method development and validation
- Technical expertise on analytical techniques, such as chromatography (GC, LC, GC-MS, LC-MS, etc), KF and spectroscopy
- Technical expertise for troubleshooting, data review and interpretation
- In-depth knowledge of pharmaceutical industry regulations and guidelines
- Expertise on GMP concepts and practices
- Strong organizational and project management skills
- Strong communication skills both oral and written
- Strong knowledge and experience in writing/reviewing analytical reports for regulatory submissions
- The ability to work successfully in both a team/matrix environment as well as independently
- Ability to work in a fast-paced environment, manage priorities, communicate outcomes and maintain timelines for multiple projects
- Attention to detail
Education and Experience:
- Ph.D. with 6-8+ years, Master’s degree with 9+ years, or BS degree with 11+ years of relevant professional analytical development experience
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]
Top Skills
What We Do
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases.
We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases.
Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston’s Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 3,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development.
Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and the British Pharmacological Society awards.
