(Senior) Research Associate, Protein Purification and Analytics - Pilsen

Company Summary:

Ampersand Biomedicines is an innovative, privately held biotechnology company leading the way in developing multi-specific medicines that direct a wide range of therapeutic molecules to specific cells and biological contexts (www.Ampersand.bio).  Ampersand was founded in Flagship Pioneering’s venture creation engine, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created.  With a strong emphasis on innovation, Ampersand cultivates a highly dynamic and entrepreneurial environment. 

Ampersand Biomedicines‘ Pilsen Team, formerly Abcheck and now a Flagship Pioneering Company, discovers and optimizes human therapeutic antibodies with one of the industry’s most versatile technology platforms. Tailored to specific needs and desired Target Product Profiles, the experienced team leverages both cutting-edge (e.g., microfluidics, rabbit mass humanization) and state-of-the-art (e.g., phage display libraries) technologies to provide high quality leads against a range of diverse targets.

Position Summary:

Ampersand Biomedicines, Inc. is looking for a highly motivated, goal-driven and collaborative Research Associate to join our dynamic Protein Sciences team.  This is a unique opportunity to help drive the development of a rapidly growing early-stage science and technology company within a well-resourced environment.  The successful candidate will play a pivotal role in advancing our research and development efforts by applying their specialized knowledge in protein sciences.  The candidate will report to a highly experienced Scientist in the Protein Sciences department and will enjoy working in a pioneering and fast-paced start-up environment.  This is a full-time on-site, laboratory-based position in Plzeň, Czech Republic.

Key Responsibilities:

• Execute protein purification using various chromatography techniques (affinity, SEC, IEX, HIC etc. with the help of FPLC)
• Thorough protein characterization (biochemical: SDS-PAGE, immuno western blot, ELISA; biophysical: BLI/SPR)
• Molecular cloning of proteins
• Implementation and documentation of dedicated experiments according to detailed protocols and standard operating procedures as well as contribution to general maintenance of laboratories and equipment

Key Qualifications:

• Biological/medical assistant or Ba or MSc in biology or related field.
• Hand-on experience with protein purification (affinity, SEC, IEX, etc.) and/or experience with biochemical and biophysical characterization of purified proteins/antibodies (SDS-PAGE, immuno western blot, ELISA, BLI/SPR, etc.) is required
• Experience in mammalian cell culture, molecular cloning or other molecular biology techniques is a plus.
• Meticulous attention to detail, good organizational skills, and strength in problem-solving.
• Aptitude and enthusiasm towards learning new techniques, improving upon existing processes, and understanding the “why” behind experimental protocols.
• Sense of responsibility in regard to experimental work, the team and the mission of Ampersand
• Adaptivity to language requirements. Our team is international, written documents like experimental protocols and records are in English language

Compensation and grade will be adjusted to the experience level of the applicant.

About Flagship

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.