Scientist- Protein Purification

Posted 5 Days Ago
Be an Early Applicant
Tarrytown, NY
93K-151K Annually
Senior level
Biotech • Pharmaceutical
The Role
The Scientist in Protein Purification will support the purification and biochemical characterization of protein reagents, conduct protein purification and characterization, and perform laboratory testing and analysis of protein results. This role requires expertise in handling protein biochemistry, including various chromatography techniques and data documentation.
Summary Generated by Built In

We are seeking a highly motivated Scientist to join our Protein Development group within the Therapeutic Proteins department. You will support purification & biochemical characterization of protein reagents.

As a Scientist, a typical day might include:

  • Conducting protein purification using an ÄKTA AVANT or Pure chromatography system 

  • Carrying out LAL (limulus amebocyte lysate) testing for bacterial lipopolysaccharide endotoxin

  • Doing protein characterization of reagents by Western blotting, SDS PAGE electrophoresis, SEC chromatography, spectrophotometry, etc.

  • Conjugating protein reagents to biotin, fluorophores (e.g. Alexa & PE), & other tags

  • Performing antibody purification working in a team for small scale production in a fast pace setting

  • Conducting protein expression in E. coli, refolding of inclusion bodies, and developing methods of protein purification

  • Interpreting data & documenting findings in electronic notebook (ELN)

This role might be for you if you:

  • Can work productively in a fast-paced collaborative team

  • Have strong organizational skills and excellent verbal and written communication skills

  • Enjoy working productively in a fast-paced collaborative environment

  • Have an eye for detail and pride yourself on the quality of your work

  • Enjoy working on current problems while thinking of future solutions.

In order to be considered for this role, you must have at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 6+ years of relevant experience in protein purification/characterization. E.coli expression and purification are required.  We need someone with a solid understanding of protein biochemistry. Must have hands on experience with Affinity, Ion Exchange, Reverse Phase, & Size Exclusion chromatography. Experience with automated liquid handlers is advantageous. Experience with Spectrophotometry, SDS-PAGE electrophoresis & Western blotting is required. Additionally, experience with the solubilization, handling, & characterization of peptides is a plus.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions.  For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process.  Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$92,500.00 - $151,100.00

Top Skills

Affinity Chromatography
Antibody Purification
Automated Liquid Handlers
Biochemical Characterization
E. Coli
Ion Exchange Chromatography
Lal Testing
Protein Expression
Protein Purification
Pure Chromatography
Reverse Phase Chromatography
Sds-Page Electrophoresis
Sec Chromatography
Size Exclusion Chromatography
Spectrophotometry
Western Blotting
Äkta Avant
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The Company
HQ: New York, New York
15,000 Employees
Hybrid Workplace
Year Founded: 1988

What We Do

At Regeneron we believe that when the right idea finds the right team, powerful change is possible. As we work across our expanding global network to invent, develop and commercialize life-transforming medicines for people with serious diseases, we’re establishing new ways to think about science, manufacturing and commercialization. And new ways to think about health. Connect with us so we can learn more about you, and you can learn more about our biopharmaceutical medicines. And join us, as we build a future we believe in.

Please visit www.regeneron.com/social-media-terms for information on how to engage with us on social media.

An important note about privacy: Regeneron is committed to your privacy and will not ask for sensitive personal information such as social security number, date of birth or bank account details via email or social media.

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