Scientist I, Proteomics

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Position

We are seeking a highly skilled Scientist with expertise in Proteomics to join Nurix’s Discovery team. Nurix is devoted to unlocking the therapeutic potential of the ubiquitin proteasome system (UPS) in oncology, immune-oncology and other therapeutic areas. The successful candidate will support Nurix’s drug discovery program and play a leading role in building and implementing proteomics capabilities. This individual will work closely with an experienced team of interdisciplinary scientists and will have regular opportunities to present findings and opinions to project teams and senior management. The ideal candidate will be self-driven, resourceful, very organized and focused, and enjoy working in a dynamic environment.

•    Utilize mass spectrometry techniques for protein identification and quantification for various sample types including complex mixtures using label-free and label-based techniques 

•    Implement new technologies, and develop proteomics workflows including sample preparation and data analyses 

•    Design proteomics-based experiments together with the project team, and lead the execution, analyses and interpretation of results 

•    Maintain and troubleshoot mass spectrometers as needed

Qualifications

•    BS, MS or Ph.D. in Chemistry, Biology or related field with 3 or more years of relevant experience 

•    Demonstrated experience in designing, executing and analyzing quantitative proteomics experiments  

•    Demonstrated expertise in operating relevant mass spectrometer instruments  

•    Knowledge of computational methods to analyze diverse mass spectroscopy datasets 

•    A proven track record with excellent interpersonal skills and ability to work in a team environment 

•    The successful candidate will be strongly aligned with Nurix’s culture and values; he/she will be team-oriented and highly collaborative with a hands-on approach 

•    The candidate should be enthusiastic, driven, and have the ability to work independently and thrive in a dynamic environment

Fit with Nurix Culture & Values:

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

Application Process

Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.

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