Colossal is looking for a talented research associate in stem cell biology with an interest in the generation, editing and differentiation of stem cells from non-model mammalian organisms. You will work closely with other lab team members in efforts to innovate on protocols of genome editing, reprogramming and lineage differentiation using cutting edge technologies.
This position is based on-site in Dallas, TX. Relocation assistance is available.
Duties and Responsibilities:
- Derive and characterize stable cell lines from primary tissues
- Test novel cell culture conditions and delivery methods to optimize gene editing
- Expand clonal cell lines for cryopreservation, genotyping and QC assays
- Develop cell assays to perform genotype to phenotype predictions
- Work with team members to integrate targeting, genotyping and QC workflows
- Schedule, analyze and execute experiments to deliver on project milestones
- Attend lab meetings, prepares reports and presentations on the progress of projects
- Demonstrate great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities:
- Experience in primary cell line derivation, culture optimization and cryopreservation
- Experience with electroporation and transfection to maximize gene delivery and viability
- Experience immunostaining cells for flow cytometry and fluorescent microscopy
- Organized and comfortable multi-tasking to deliver on concurrent projects on time
- Strong written and oral communication skills, as well as creative problem-solving skills
Preferred Skills and Abilities:
- Experience with high throughput imaging platforms and data analysis
- Experience gene editing and expanding iPSCs for clonal cell line derivation
- Experience in molecular biology (DNA, RNA, protein extraction, qPCR etc)
Education and Experience:
- BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.
What Colossal Offers You:
- Medical, dental, and vision coverage
- Unlimited PTO and company holidays so you can rest and recharge
- Flexible spending accounts (FSA)
- Company matched 401k retirement plan
- Paid parental leave up to 12 weeks
- Education reimbursement
- An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in three locations that include laboratories, test facilities, academic institutions, libraries and offices. Dallas. Austin. Boston.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:
- #1 on the 50 Best Startups to Work For in Dallas in 2023!
- 100 Best Midsize Places to Work in Dallas in 2024 & 2025
- 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 & 2025
- 100 Best Midsize Places to Work in Boston in 2024 & 2025
Built In 2025 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!
What We Do
Colossal is a breakthrough bioscience and genetic engineering company that builds radical new technologies to advance the field of genomics. Colossal creates disruptive technologies for extinct species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. The company is the first to apply CRISPR technology for the purposes of species de-extinction, beginning with the woolly mammoth. Colossal is accepting humanity’s duty to restore Earth to a healthier state.
Why Work With Us
Colossal will revolutionize history and be the first company to use CRISPR technology successfully in the de-extinction of previously lost species. On the journey we will build radical new software tools and technologies to advance the science of genomics overall. Join our team and be proud of your contribution to science and the planet.