Totus Medicines is a clinical-stage biotechnology company pioneering precision small molecule therapies to transform treatment paradigms in oncology, immunology, and inflammation (I&I). Our proprietary OmniDEL platform, powered by a novel DNA-encoded covalent library and advanced AI/ML integration, enables the simultaneous screening of hundreds of millions of drug candidates against multiple targets. This innovative approach allows us to identify promising therapies for previously undruggable and difficult to drug targets.
We are seeking a self-motivated and detail-oriented Research Associate in the field of protein sciences within the Totus research group. This is a contract position for 6 -12 months.The successful candidate will produce and characterize a wide variety of disease relevant proteins while working in multi-disciplinary team, with ample opportunities to learn cutting-edge science.
Responsibilities and Expectations
- Cell biology: maintain, track, and transiently transfect mammalian cells in parallel
- Protein production: measure overexpression using a variety of techniques
- Harvest: aliquot, store, and inventory host cells for downstream use
- Document results in an ELN in a detailed and timely manner
- Open to learning new techniques
- Actively contribute to a culture of scientific excellence and integrity
Qualifications
- B.S. degree in cell biology, biochemistry, bioengineering, or a related discipline, with 1+ year of laboratory experience
- Strong organizational and communication skills; ability to prioritize tasks and manage time effectively; attention to detail and documentation
- Excellent laboratory and sterile technique
- Hands-on experience with mammalian cell culture
- Hands-on experience in protein production, preferably from mammalian host cells
- Hands-on experience in protein analytics, including SDS-PAGE, Western blot, and plate based spectroscopic and luminescent assays
- Familiarity with automated Simple Western instruments (Leo, Jess, Abby) is a plus
Top Skills
What We Do
Totus Medicines is applying revolutionary chemical biology technologies to create life-changing covalent therapeutics for untreatable diseases.
