Research Associate PD / Scale-up Bioconjugates

Research Associate PD / Scale-up Bioconjugates / Synnafix

Location: Oss

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Lonza acquired Synaffix, a biotechnology company focused on commercializing its clinical-stage technology platform for the development of more effective and better tolerated antibody-drug conjugates (ADCs.)

As a Research Associate PD/ Scale-up Bioconjugates you will operate in a team that supports process development and scale-up of ADC production for early phase collaborations with biotech/pharma companies. The key tasks include; setting up experiments, running reactions and purifying intermediates and final products and interpretation of results. In addition you will characterize the produced ADCs with various analytical tools.

What you’ll do:

• Execution of experiments following established protocols (including but not limited to performing remodeling and bioconjugation experiments, product purification, product fill-finish and product analysis).

• Perform DoE experiments and interpretate the data.

• Perform proof of concept runs (PoC runs).

• Processing, analyzing & documenting of results in ELN.

• Take assigned responsibilities in designated tasks & projects.

• Preparation of production reports and product certificates.

• Provide general support to lab operations.

• Adhere to company policies and quality & safety standards.

What we’re looking for:

• Master of Science (M.Sc.) in a relevant field, preferably in chemical biology, biochemistry, biomedical engineering.

• 1 -4 years relevant work experience in Pharma / Biotech area.

• Experience with various protein purification and analysis techniques including TFF, IEX, affinity chromatography (protein A/L, Ni-NTA), SEC, SDS-PAGE, RP-HPLC and MS.

• Experience with handling antibodies, including modification, purification and analysis.

• Familiarity with various bioconjugation chemistry techniques and preferably hands-on experience.

• Strong commitment to laboratory work and project delivery.

• Attention to detail and accuracy.

• Strong team-player mentality.

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.