About Us
Jnana Therapeutics, a wholly owned subsidiary of Otsuka Pharmaceutical, is a clinical-stage biotechnology company leveraging its next-generation RAPID chemoproteomics platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet needs. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases and immune-mediated diseases. Jnana’s lead program, JNT-517, which targets an allosteric site on the phenylalanine transporter SLC6A19, is a potential first-in-class oral approach for the treatment of PKU, a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, and a highly experienced management team. For more information, please visit www.jnanatx.com and follow us on Twitter/X and LinkedIn.
At Jnana, you'll join a diverse, passionate team dedicated to advancing therapies for challenging diseases. Our collaborative, purpose-driven culture fosters innovation, urgency, and belonging—making Jnana a great place to work!
About the Opportunity
As a Research Associate in our Chemical Biology group, you will support a range of mass spectrometry-based activities by developing and running bioanalytical methods and assays for multiple programs at various stages.
The ideal candidate is enthusiastic, creative, and motivated by a career in analytical drug discovery. You should have a strong foundation in mass spectrometry and its applications in a drug discovery setting. Prior experience in drug discovery and bioanalysis is preferred, but training will be provided for candidates with strong potential. Level can be flexible based on experience.
Responsibilities
- Prepare samples for general bioanalytical and ADME assessments for mass spectrometry-based analysis.
- Develop and validate analytical methods to quantify small molecules and metabolites from various biological matrices.
- Assist with routine maintenance and upkeep on mass spectrometers and liquid chromatography systems to ensure they are operating at peak performance.
- Efficiently generate, analyze, and present data reports to project teams, as well as upload to the internal database.
- Work closely with project teams in the design and execution of studies supporting discovery programs, prioritizing work for execution against timelines.
- Commitment to ongoing professional growth and a passion for driving innovation.
- Opportunities to expand expertise in mass spectrometry-based proteomics assays.
Preferred Qualifications & Experience
- Bachelor’s degree with approximately 2 years related experience in the contract research or pharmaceutical industry.
- Experience with both Thermo Fisher and Agilent instrumentation/software is desirable.
- Self-starter and eager to learn new skills and techniques.
- Ability to work effectively both independently and collaboratively within a team.
- Proficiency in the use of standard software including Microsoft Excel, Word, PowerPoint, etc.
Top Skills
What We Do
Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation chemoproteomics RAPID platform to discover medicines for highly validated, challenging-to-drug targets to treat diseases with high unmet need. Jnana is focused on developing first- and best-in-class therapies to treat a wide range of diseases, including rare diseases, immune-mediated diseases and cancer. Jnana’s wholly owned lead program is a potential first-in-class oral approach, targeting an allosteric site on the phenylalanine transporter SLC6A19, for the treatment of phenylketonuria (PKU), a rare genetic metabolic disease. Located in Boston, Jnana brings together scientific leaders in small molecule drug discovery and development, a highly experienced management team and the backing of leading life science investors Bain Capital Life Sciences, RA Capital Management, Polaris Partners, Versant Ventures, Avalon Ventures, Pfizer Ventures and AbbVie Ventures. For more information, please visit www.jnanatx.com and follow us on Twitter and on LinkedIn.