Post Doctorate Scientist

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

At Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision and action. And we believe that good business means a better world.

That is why we come to work every single day. We commit ourselves to scientific rigour, unassailable ethics and access to medical innovations for all. We do this today to build a better tomorrow.

The opportunity

We are seeking a highly motivated postdoctoral fellow to join the Immunology Discovery group of the Cardiovascular Metabolism and Immunology Department, located in Basel, Switzerland. We are seeking an independent and highly motivated researcher to advance our understanding of the mechanisms underlying the progression of inflammatory bowel diseases (IBD). Specifically, the research project will aim at investigating the role of T cell plasticity in maintaining intestinal homeostasis and in the development of chronic and tissue-damaging intestinal inflammation. 

In this position you will:

• Alone and in collaboration with data scientists, analyze multi-omics data sets including scRNAseq, TCRseq, 16Sseq, metabolomics and identify molecules to be tested in vitro;

• Develop methods for isolation of immune cells from blood and tissue;

• Perform detailed immune phenotyping of cell populations of interest using multicolormulti-color flow cytometry;

• Perform sophisticated in vitro 3D cultures, including organoids, of human and mouse cells;

• Investigate the impact of bacterial isolates and/or metabolites on host immune, epithelial and stromal cells;

• Carry out in vivo studies to further mechanistic understanding;

• Form close collaborative relationships with other scientists within the CMI Department and technical teams in other functions.

Who you are:

• You hold a PhD in immunology obtained no longer than four years ago.

• You have a profound understanding of human immunology, mucosal immunity and T cell biology.

• You have extensive experience with state-of-the-art flow cytometry, including FACS.

• You have a track record of hands-on experience with isolation and cultivation of human immune cells.

• Experience with in vivo models of inflammation is a plus.

• Experience in data analysis using R or Python is a plus.

• You have very good interpersonal and communication skills, are able to build good working relationships and are an outstanding teammate. 

• Your experience and investigative attitude allow you to work independently, to design, perform and interpret experiments and to embark on new scientific methodologies.

• You published as a leading author in top-tier journals.

• You have a strong team spirit, and you like to work in international teams

• Your excellent English skills, written and spoken, complete your profile.

This position is sponsored by the Roche Postdoctoral Fellowship Programme.

The RPF Programme has the ambition to build and maintain the Scientific Leadership of the future and to provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers, and leading academic research groups, from around the world. One of the key aims is to advance basic science and technologies that will be published in top-rated, peer-reviewed scientific journals, if necessary preceded by priority patent applications. 

The duration of the RPF project is initially set for two years, with the possibility of extension for a third year. You will be based in Basel, Switzerland.

The start date of this fellowship is as soon as possible. Please clearly indicate your preferred starting date in your motivation letter. All applications always need to include a CV, motivation letter, the copy of your degree, and a publication list.

Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq

More information about the RPF Program: https://www.roche.com/careers/workplaces/wp_research/the-roche-postdoctoral-fellowship-programme.htm

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.