Science is a clinical stage, vertically integrated technology company focused on solving some of neuroscience’s hardest questions and most serious unmet medical needs. We work to restore quality of life to those with debilitating conditions for which there are no treatment options, creating devices aimed at restoring vision, cognition, and mobility to patients who have lost it. To support progress across our industry, we provide state-of-the-art components and vertically integrated infrastructure for others to build on via Science Foundry.
We are developing a biohybrid brain-computer interface to increase the number of interface channels by several orders of magnitude. We are extending our pilot work on this subject, recently posted on bioRxiv, to develop a fully integrated cell-device hybrid that can potentially achieve over a million single-unit interface channels with the brain. We are looking for experimental neuroscientists enthusiastic about performing collaborative research to develop a transformative approach to brain-computer interfaces.
Candidates can look forward to becoming a key contributor in a talented, driven, and interdisciplinary team working to develop prototype devices and explore their functional properties. Ideal candidates will have extensive experience performing cranial surgeries in rodents, collecting and analyzing in vivo electrophysiology datasets, and performing multiphoton microscopy. Additional qualifications include proficiency with scientific computing for experimental control and data analysis, histology, and experience with animal behavior.
Role responsibilities:
- Perform cranial surgical implants for studies on graft integration and device development
- Perform in vivo electrophysiology with both commercial and custom brain probes
- Perform and analyze live 2P imaging to assess graft survival, integration, and activity develop strategies to promote neuron graft survival and integration
- Develop experimental approaches to test physiology of graft integration
- Develop strategies to promote graft survival
- Analyze experiments and present results
Key qualifications:
- A track record of excellence and creativity in your field as demonstrated by publications, patents, success with commercialization or translation, or other notable achievements
- Expert level proficiency with rodent cranial surgeries and aseptic techniques, including installation of cranial windows and intracortical injections.
- Expert level proficiency working with conventional in vivo electrophysiology probes (e.g. neuropixels)
- Expert level proficiency working with scientific computing packages to control online experimental control and analyze data
- Thrives when working collaboratively and tackling difficult technical challenges
- Excellent communication skills
- Commitment to a respectful and supportive work environment
Preferred qualifications:
- PhD in Neuroscience
- Proficiency with mammalian cell culture
- Direct experience transplanting stem cells into the nervous system
- Practical experience with histopathology materials and methods
- Experience training animals and performing quantitative animal behavior experiments
Salary/Pay Range:
Science is required under California law to include a reasonable estimate of the compensation range for this role. We determine your level based on your interview performance and make an offer based on the indicated salary band. The base salary range for this full-time position is $90,000 – $130,000 annually + equity + benefits. Within the range, individual pay is determined by several factors, including job-related skills, experience, and relevant education or training. Please keep in mind that the equity portion of the offer is not included in these numbers.
Benefits:
At Science, our benefits are in place to support the whole you:
- Competitive salary and equity
- Medical, dental, vision and life insurance
- Flexible vacation and company-paid holidays
- Healthy meals and snacks provided for non-remote employees
- Paid parental, jury duty, bereavement, family care and medical leave
- Dependent Care Flexible Spending Account, subsidized by Science
- Flexible Spending Account
- 401(k)
Science Corporation is an equal opportunity employer. We strive to create a supportive and inclusive workplace where contributions are valued and celebrated, and our employees thrive by being themselves and are inspired to do their best work.
We seek applicants of all backgrounds and identities, across race, color, ethnicity, national origin or ancestry, citizenship, religion, sex, sexual orientation, gender identity or expression, veteran status, marital status, pregnancy or parental status, or disability. Applicants will not be discriminated against based on these or other protected categories or social identities. Science will also consider for employment qualified applicants with criminal histories in a manner consistent with applicable federal, state and local law.
Top Skills
What We Do
Science is an early stage company developing technologies for a range of serious unmet medical needs. We are unafraid to take difficult technical risks, secure in the knowledge that with a clear understanding of what we are doing and with support from powerful modern tools, more progress is possible than might be immediately obvious.
