High-throughput ADME Screening Group Lead

Posted Yesterday
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2 Locations
168K-295K Annually
Expert/Leader
Healthtech • Biotech • Pharmaceutical
The Role
Lead a cross-site ADME Screening team, focusing on early tier screening assays, collaboration, and technology integration for drug discovery.
Summary Generated by Built In

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Investigative ADME/Toxicology and BioAnalytical Research (BAR) group is an organization purpose-built team to ensure we provide stage-appropriate, problem-focused to molecular creation teams that make life better for people. We focus on using innovative science to unlock new approaches that can treat people suffering from diseases with poor treatment options. We continually challenge ourselves to deliver molecules that can provide breakthrough efficacy with the highest possible safety margins. We are committed to continually optimizing our approach, technology and processes to improve our speed of execution. We relentlessly pursue a culture anchored in empowering scientists and teams to innovate and advance projects through deep collaboration and personal accountability.  

 

Position Summary:   

 

The Investigative ADME/Toxicology and BioAnalytical Research team focuses primarily on drug discovery using both traditional and novel scientific approaches. We seek an experienced leader for our cross-site ADME Screening team. The candidate should have a passion for developing capacity enabling early tier screening assays which deliver reliable results at the pace discovery research demandsThe candidate should demonstrate a record or leading groups across multiple sites while maintaining a deep knowledge of current technology to solve draggability challenges across modalities. Collaboration with ADME project leaders, lab-based scientists and medicinal chemists is essential. This role requires excellent people skills, a positive attitude, willingness to learn, attention to detail, and the ability to thrive in a fast-paced team environment. 

Responsibilities: 

  • Lead a cross-site team of Screening ADME scientists, primarily focused on the support of the new Lilly Small Molecule Discovery (LSMD) group, but one that can also provide support to LRL therapeutic areas and molecular creation teams (LGM, and BioTDR). 

  • Establish a stage-oriented, high-capacity screening team focused on cross-site integration, execution and organizational effectiveness for team members primarily in Indianapolis and Colorado. 

  • Ensure on-demand, problem-focused screening is accomplished in support of programs in discovery and amplify project takeaways to improve performance primarily within discovery.   

  • Work with other leaders across the Investigative ADME/Toxicology and BioAnalytical Research organization to ensure critical success factors are outlined for teams, while working to provide prompt delivery which will include assay development, data analysis and reporting.   

  • Provide guidance and next-level mentorship to members of the Screening ADME team.   

  • Champion an environment that challenges the organization to actively tackle challenging problems, while evaluating/internalizing new technology to increase efficiency and excellence to the group. 

 

Basic Requirements: 

  • PhD with minimum of 10+ years academic/research/industry exp (may include post-doc experience), MS with 15+ years industry/academic/research exp, or BS with 20+ years industry/academic/research experience within the pharmaceutical sector, or a closely related field. 

  • Demonstrated experience with key technologies, including automated liquid handling, high speed liquid chromatography–tandem mass spectrometry (LC-MS/MS) for sample analysis, and software and automation tools to support the throughput and capacity required for early phases discovery assay support. 

 

Additional Preferences: 

  • In-depth knowledge of hit-to-lead to candidate optimization across the ADME field.  Other field expertise a plus. 

  • Proven ability to collaborate across fields to achieve project goals and timelines. 

  • Flexible in prioritizing to meet organizational and scientific objectives. 

  • Works independently and as part of a team. 

  • Highly organized with strong analytical, documentation, time management, and multi-tasking skills. 

  • Sees personal success as part of team success. 

  • Hard-working and data-dependent decision maker. 

  • Anticipates challenges and proactively proposes solutions. 

  • Adaptive and applies creative problem-solving to meet needs. 

  • Capable of leading with team empowerment and consensus. 

 

Additional Information: 

Physical Demands/Travel: 

The physical demands of this job are consistent with a lab and office environment.    The role may require travel to ensure an integrated team across US-based sites.

Work Environment: 

This position’s work environment is in a Laboratory and office  

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.


Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$168,000 - $294,800

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

#WeAreLilly

Top Skills

Automated Liquid Handling
High Speed Liquid Chromatography
Software And Automation Tools
Tandem Mass Spectrometry
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The Company
HQ: Indianapolis, IN
39,451 Employees
On-site Workplace
Year Founded: 1876

What We Do

Eli Lilly and Company engages in the discovery, development, manufacture, and sale of products in pharmaceutical products business segment.

For more than a century, we have stayed true to a core set of values – excellence, integrity, and respect for people – that guide us in all we do: discovering medicines that meet real needs, improving the understanding and management of disease, and giving back to communities through philanthropy and volunteerism.

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