Director, Physiological Systems

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way?

About Vesalius

Vesalius Therapeutics is pioneering a revolutionary platform to generate breakthrough treatments for common diseases.  Vesalius’ platform uses large-scale human genetics, genomics, stem cell studies and artificial intelligence to uncover causal biology and identify optimal intervention points for new therapies. Efficiently identifying these intervention points and the patients most likely to benefit from these novel therapies will enable smaller, shorter clinical trials with a higher probability of success. Vesalius was founded in 2019 by Flagship Pioneering. For more information visit vesaliustx.com, or follow us on X and LinkedIn.

About the Position

Vesalius Therapeutics is seeking a highly accomplished leader to build next-generation physiological models from human cells, with initial focus on the central nervous system. All models are false; few are useful. You will lead our efforts to change that by developing new, reliable human-based models of the physiological processes underlying disease. You will expand and lead a world-class team in stem cell biology, tissue engineering, and disease biology to deliver new, physiologically faithful models of the biological underpinnings of disease.

Responsibilities

• Design, develop and implement new mono- and multi-cellular models of physiological processes relevant to disease.
• Develop new approaches to assessing the relevance of cellular and physiological models to human disease states.
• Evaluate and introduce new, relevant technologies to the company, and champion their use in our discovery efforts. 
• Be a strong voice in the development and implementation of our target discovery platform. 
• Assemble and lead a team of skilled scientists to execute this mission, and collaborate across our diverse group of scientific disciplines to develop new ideas. 

Qualifications 

• PhD in a biological discipline with at least 5-8 years of relevant experience in an industry or academic setting. Additional qualifications, including MD, are considered advantageous. 
• An outstanding reputation in your field as a creative scientist, a technology innovator, and as a dynamic leader, evidenced by publication track record and/or patent filings. 
• Deep expertise in stem cell and molecular biology, preferably in the CNS.
• Extensive experience with cell-based assay development and screening using a variety of readout technologies.  
• Strong quantitative intuition, excellent data analysis skills, and experience with laboratory automation.  
• Direct supervisory experience (5+ years) leading a team of scientists (including PhD-level scientists) and a track record of recruiting, mentoring, and developing top talent.  
• Outstanding communication, collaboration, networking, and program leadership skills.  
• Demonstrated ability to work in a dynamic environment with a sense of urgency and creativity and focus on deliverables.

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Vesalius is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

At Vesalius, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Vesalius Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Vesalius or its employees is strictly prohibited unless contacted directly by the Vesalius internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Vesalius, and Vesalius will not owe any referral or other fees with respect thereto.