Chief Development Officer, Inflammation & Immunology (I&I)

ROLE SUMMARY
Reporting to the Chief I&I Officer, the Chief Development Officer I&I will be a key member of the Pfizer's I&I Leadership Team. The CDO will be responsible for leading all clinical activities in the I&I organization. They will oversee an annual budget, establish and maintain the overall clinical development strategy for the organization, and will be accountable for study delivery, long-range planning and major initiatives.
This is a critical and strategic senior leadership role in the delivery of Pfizer's I&I portfolio strategy; the CDO will have a direct and lasting impact on overall corporate performance. They will be accountable for all early and late-stage clinical development activities, from first-in-human studies through post-marketing. They will set a compelling and convincing vision for Pfizer I&I to drive the advancement of the pipeline and portfolio of all early, late stage and marketed therapies and maximize portfolio value with speed, high quality and cost-consciousness. Specifically, the CDO will contribute to the prioritization of the end-to-end portfolio with an emphasis on selection of molecules/medicines that have the greatest likelihood to bring transformative benefit to patients and bring value to Pfizer. This role will support and lead the execution of all clinical studies and accelerate drug development where possible through innovative trial design.
ROLE RESPONSIBILITIES

• Deliver clinical development of medicines and regulatory approvals for I&I across the portfolio
• Set value creation objectives that realize the end-to-end therapeutic area strategies and provide an appropriate return on investment
• Foster strong collaboration with external partners, including academic institutions, contract research organizations (CROs), and key opinion leaders (KOLs), to enhance Pfizer's I&I clinical development capabilities
• Represent the company at scientific conferences, regulatory meetings, and other academic and industry events, presenting clinical data and strategies, and engaging with key stakeholders to enhance the company's reputation and visibility
• Maintain current knowledge in emerging areas of medicine, including review of the science, competition, key opportunities, as well as advise on new, evolving technology, innovations, and practices in drug development.
• Stay abreast of the latest advancements in I&I research and clinical development and apply scientific and clinical expertise to drive innovation and excellence in clinical programs
• Provide development expertise and strategic guidance across business development activities

The CDO, I&I will also have direct operational oversight and line responsibility for the functions supported within the Pfizer I&I Division:

• Medicine Team Leads
• Global Clinical Leads
• Category Clinicians
• Clinical Scientists

The I&I Clinical R&D organization plays a key role in delivering the I&I global portfolio. Colleagues bring science and data analytics together to support various aspects of the drug development process, from clinical trial execution, data acquisition, data review, statistical analysis and reporting, regulatory affairs, and submissions.

• The CDO I&I will partner closely with the Head of
• Preclinical to support prioritization of the early portfolio, and supporting optimization of FIH readiness.
• They will also partner closely with the Head of Clinical Development & Operations, allowing efficient execution of studies, with high quality and completeness of data

QUALIFICATIONS
The successful candidate will bring an impressive and industry-leading track record in I&I drug development.
In terms of the performance and personal competencies required for the position, we would highlight:

• M.D. and/or Ph.D credentials are required together with significant experience in I&I clinical development; experience working in both pharma (complexity) and biotech (nimble) companies would be ideal
• Well-respected and recognized industry leader with a proven track record of leading large-scale matrixed, global I&I clinical development teams that have successfully advanced assets to commercialization; experience in late stage development and regulatory / filing experience is key. Translational and Early Development experience or aptitude is necessary, as is fluency in preclinical development enabling clinical entry
• Track record in developing multi-indication I&I blockbuster products. Ideally has experience in dermatology, gastroenterology, respiratory and rheumatology.
• Modality experience in small molecules, and biologics, including multispecific antibodies would be highly valued
• Excellent leadership and interpersonal skills to quickly build rapport and credibility with Pfizer leaders and key external stakeholders, including exhibiting a strong commitment to Pfizer's Values and Behaviors
• Experience in managing the interfaces with discovery, translational/early development, medical, safety and clinical operations organizations
• Strong knowledge of relevant FDA regulations and guidelines as well as those of the EU, Japan, China and other global health authorities
• Connected with key stakeholders globally (regulators, KOLs, universities, VCs, biotechnology companies, clinical community, patient groups, policymakers)
• History of smart decision making, placing strategic bets, making tough portfolio and resource allocation decisions, in order to maximize return on investment
• Has the gravitas, confidence, and executive presence to operate with business leaders / C-suite stakeholders and stakeholders and influencing high level R&D decisions in a clear, concise and impactful manner
• Excellent track record of operational management, process improvement and business development

ORGANIZATIONAL RELATIONSHIPS
Stakeholders across the I&I end to end organization, Commercial, Business Innovation, Clinical Development & Operations , Statistics, Clinical Pharmacology, Preclinical and Translational Sciences, Finance, People Experience.
OTHER INFORMATION
Financial Accountability
In partnership with the Chief I&I Officer will oversee a budget up to 500 million
Supervision
Will manage a team of up to 60 colleagues
The annual base salary for this position ranges from $330,000.00 to $0.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 45.0% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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